CAS 89778-27-8 Anti Estrogen Drugs Fareston Toremifene Citrate 598.09 Molecular Weight

CAS 89778-27-8 Anti Estrogen Drugs Fareston Toremifene Citrate 598.09 Molecular Weight​

Anti Estrogen Steroids:

Quick detail:

Product Name	Toremifene Citrate
Chemical Name	Fareston
CAS Number	89778-27-8
Molecular Formula	C26H28ClNO
Molecular Weight	598.09
Molecular Structure
Melting Point	160-162℃
Assay	99.5%
Appearance	White powder

Description:

Toremifene (also known under its brand and trade name of Fareston) is a member of a category, family, and class of drugs that are known as SERMs (Selective Estrogen Receptor Modulators). SERMs fall under an even broader category of drugs that are known as anti-estrogens, and the cousin family of SERMs (that also fall under anti-estrogens) are aromatase inhibitors, commonly abbreviated as AIs. SERMs include compounds such as Toremifene, Nolvadex (Tamoxifen), and Clomid (Clomiphene Citrate). Aromatase inhibitors (AIs) include compounds such as Arimidex (Anastrozole), Aromasin (Exemestane), and Letrozole (Femara). Although the two fall under the category of anti-estrogens, they are both sub-categories that branch off into their own families, as SERMs and AIs differ greatly in their mechanism of action within the human body concerning how they control or block Estrogen. There has been much misunderstanding and misconception in previous decades as to what each of these do, and this should always be first clarified to the reader before describing Toremifene.

Application:

Toremifene citrate is an oral selective estrogen receptor modulator (SERM) which helps oppose the actions of estrogen in the body. Licensed in the United States under the brand name Fareston, toremifene citrate is FDA-approved for use in advanced (metastatic) breast cancer. It is also being evaluated for prevention of prostate cancer under the brand name Acapodene.

It has already been covered that Toremifene is a SERM, and serves to block Estrogen at various receptor sites in certain tissues within the body (breast tissue in particular). As a layman explanation, Toremifene pretends to be a 'fake' Estrogen that occupies Estrogen receptors within breast tissue. With these receptors occupied by Toremifene, real Estrogen cannot perform their jobs there. Toremifene does not reduce total blood plasma levels of Estrogen. In addition to being antagonistic to Estrogen receptors in breast tissue, it is also antagonistic to Estrogen at the hypothalamus gland (this essentially 'tricks' the hypothalamus into thinking there is little or no circulating Estrogen levels in the body, causing it to increase its manufacture of Testosterone so that it can utilize aromatization to restore these levels

COA:

Dosages:

For bodybuilding purposes, a dose of 40-60mgs per day seems to be a good starting point. If the user is trying to fight existing gynecomastia (bitch tits), they may choose to double the dose and add an aromatase inhibitor like Aromasin with it. For PCT, some users will kick-start with 100-120mgs per day and then lower to 40-60mgs per day for 4-6 weeks.

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