Clomid CAS 50-41-9 Popular Raw Powder Clomiphene Citrate 99.4% High Purity

Clomifene Citrate

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Description:

Clomid (Clomiphene Citrate) is a powerfully effective anti-estrogen officially classified as a Selective Estrogen Receptor Modulator (SERM). In many ways, it is very similar to another popular SERM in Nolvadex (Tamoxifen Citrate). It can also be used as a Post Cycle Therapy (PCT) medication in order to stimulate suppressed testosterone production due to anabolic steroid use. PCT use of Clomid is the most common purpose and most beneficial point of use for the anabolic steroid user.

Clomiphene Citrate is a SERM that is specifically used as a fertility aid due to its ability to enhance the release of gonadotropins. Clomid has the ability to oppose the negative feedback of estrogens on the Hypothalamic-Pituitary-Ovarian-Axis. This will increase the release of Luteinizing Hormone (LH) and Follicle Stimulating Hormone (FSH) significantly.

By increasing gonadotropin release, this can lead to the egg being released, thereby increasing the chance of conception.

As a SERM, Clomid will not serve to block or reduce any other Estrogenic side effects, however, as it serves only to block Estrogenic activity at the breast tissue area (when major Estrogenic side effects are concerned). Clomid does not (nor do any SERMs) serve to reduce bloating, water retention, rising blood pressure (as a result of water retention), or acne formation – these are all side effects resultant from increasing blood plasma Estrogen levels.

There are no special considerations for clomiphene administration. It can be administered before, during, or following meals. It may also be consumed in the morning or at night before bed. There should be no reason to split up the clomiphene dosage throughout the day, as clomiphene’s half-life is about 5-7 days, which is considered long enough to maintain stable blood levels over a 24-hour (or longer) period without having to split up tablets or dosages.

Clomifene (INN) or clomiphene (USAN) (trademarked as Androxal, Clomid and Omifin, citrate salt Serophene) is a selective estrogen receptor modulator (SERM) of the triphenylethylene group that has become the most widely prescribed drug for ovulation induction to reverse anovulation or oligoovulation.

Clomifene is useful in those who are infertile due to anovulation or oligoovulation. Evidence is lacking for the use of clomifene in those who are infertile without a known reason. In such cases, studies have observed a clinical pregnancy rate 5.6% per cycle with clomifene treatment vs. 1.3%–4.2% per cycle without treatment.

Clomifene has also been used with other assisted reproductive technology to increase success rates of these other modalities.

Clomifene can be initiated at a dose of 50 mg daily for 5 days, starting on cycle day 3, 4, or 5 (where cycle day 1 is the first day of the menstrual period), thus being taken on cycle days 3-7, 4-8 or 5-9. During a clomifene-induced cycle, there should be frequent intercourse (every other day) the week before and including the estimated day of ovulation, (cycle days 9-18). If LH surge detection tests are used, these tests should be started 3 to 4 days after the last clomifene tablet is taken (that is, if taking clomifene on cycle days 4-8, LH surge tests should be started on cycle day 11) and continue until ovulation is indicated (that is, the test becomes positive.) or through cycle day 18. If there is no spontaneous surge, there may be an artificial triggering of oocyte release if there is an ovarian follicle of over 20 mm in size, such as by an intramuscular injection of 10,000 units of hCG. However, routinely using oocyte release triggering with hCG appears to decrease pregnancy chances compared to frequent monitoring with LH tests.