MOTS-c 5mg Anti Aging And Weight Loss High Purity Peptide CAS 1627580-64-6

MOTS-c Anti Aging And Weight Loss High Purity Peptide CAS 1627580-64-6 MOTS-c 5mg

MOTS-c

Product Description:

MOTS-c (human) is one of the mitochondria-derived peptides (MDP). The main physiological function is to promote the biosynthesis of endogenous AMP analogue AICAR, thereby promoting AMP-activated protein kinase (AMPK), and at the same time, it can increase the glucose uptake demand of induced cells and improve insulin sensitivity. As a drug raw material, it can be regarded as a potential weight-loss polypeptide raw material, and it also has a good anti-aging effect.

In March 2015, the journal Cell Metabolism reported that MOTS-c, a polypeptide hormone derived from the mitochondrial genome, plays an important role in the homeostasis of metabolism. MOTS-c is a polypeptide containing only 16 amino acids. Studies have shown that it mediates mitochondrial regulation of insulin through the folate-purine-AMPK pathway. new ideas. And the function of the hormone has been partially confirmed by mouse experiments.

Since the publication of the report, the research on this short peptide has been very hot. In order to support the scientific research work in this field, our company has designed and developed a complete set of research products for MOTS-c.

First, we synthesized the MOTS-c peptide (CPX132Hu01) with a newly purchased peptide synthesizer, and its amino acid sequence is: MRWQEMGYIF YPRKLR. Due to the uniqueness of the peptide sequence and structure, the peptide can be used in animal experiments to study the function of MOTS-c.

Then, based on the small molecule coupling technology, the synthesized polypeptide was connected to the coupling carrier to obtain the whole antigen BSA-MOTS-c (CPX132Hu11) and OVA-MOTS-c (CPX132Hu21), etc., which were screened after immunizing animals with the whole antigen Specific antibody (PAX132Hu01). This type of antibody can be used in various molecular and immunological experiments, such as Western Blot, IHC, etc., to qualitatively detect the content of MOTS-c in samples.

On the basis of synthetic peptides and specific antibodies, we prepared a MOTS-c quantitative detection kit (CEX132Hu) by competitive inhibition method, which can be used for the quantitative detection of MOTS-c in various biological samples.