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Andarine, commonly known as S4 and GTX-007, is a Selective Androgen Receptor Modulator (SARM) developed by GTx. Like all SARM's S4 was developed in the treatment of muscle wasting diseases with benign prostatic hypertrophy treatment also being high on the list of possible treatment benefits. Andarine is not as strong as some of the other SARM's in terms of an anabolic effect that leads to the promotion of lean muscle tissue increases, but it does appear to have other benefits that can prove to be highly valuable. Being an effective SARM, like most SARM's it is relatively side effect friendly with most users making it an increasingly common option for performance enhancing athletes.
The effects of Andarine (S4) can range from bulking to cutting and total body transformation; however, bulking (muscle/mass gains) will be the weakest of the three areas. S4 is not known for packing on a lot of lean muscle tissue, but lean gains can and should be made providing enough calories are present along with muscular stimulation (exercise). For the off-season athlete looking to really pack on size, this is not a product they'll want to base their plan around although it could be a solid addition to a plan, simply not a standalone item. Andarine is well known for aiding in strength increases. Increasing strength can be a benefit when trying to grow as it allows the individual to lift heavier weights. However, strength and size do not always go hand-in-hand and cannot be used as a gauge when trying to grow. It is very possible to gain little to no weight and still increase strength despite no increases in size.
Cutting will be where Andarine (S4) really stands out and for several reasons. The primary objective of any cutting plan is to lose body fat. In order to lose body fat one must burn more calories than he consumes, which will put lean muscle tissue at risk. S4 supplementation can provide the means to protect muscle tissue during a calorie deficit. The more tissue that's preserved, the stronger the metabolism will continue to burn. If tissue is lost, the metabolism can slow making fat loss more difficult. Some data has also shown S4 to directly increase lipolysis (fat loss) although it is unclear how significant this affect is. Equally beneficial to the cutting plan, Andarine has been shown to increase hardness and definition significantly in a lean physique. Hardening and strength effects of this SARM have often been compared to the anabolic steroid Winstrol. As an added bonus, with the strength increasing traits of S4, while strength may not increase when cutting, if using this SARM you may very well find you maintain a lot more of your strength that would have otherwise diminished.
For the every day fitness enthusiast, this may be one of the best SARM's on the market. It's not possible to gain a massive amount of muscle and shred up with any product. If you want to go to the extreme in either direction, you have to pick one direction at a time. But if you're looking for more of a transformation, not necessarily large increases in size or ripped to the bone but more of a beach body look with increases in athletic performance, this is one of the better SARM's available. Due to the side effect friendly nature, it's also one of the more appealing.
How it works?
Andarine binds incredibly well to the androgen receptors of bone and muscle. While it doesn't tend to impress in terms of building pounds upon pounds of muscle like trenbolone will, it has amazing effects on fat loss. Why? Andarine is the least anabolic, yet most androgenic of the SARMS. When androgenic hormones or sarms attach to the androgen receptors in your adipose tissue or fat (yes we have androgen receptors in our fat too) they trigger fat oxidation.
This SARM is selective and shows no noticeable prostate activity. Andarine proved to be poor at building muscle tissue at lower doses, but it did, in fact, build lean hard muscle tissue at higher doses. These tissue gains have often been compared to that of winstrol or anavar, but, of course, without the associated androgenic side effects. Andarine is especially outstanding at strengthening, preserving and even building bone mass.
Andarine's exceptional ability to help oxidize fat and keep your body from going catabolic while on a low calorie diet is its specialty. It will provide a hard, dry, lean look and increase vascularity. It provides notable strength and endurance even while in caloric deficit, and, at higher doses, it can even add hard muscle to your frame. Any other SARM stacks wonderfully with andarine, and the results will be compounded due to their synergistic effects. A stack of Andarine and ostarine (mk-2866), for example, would provide results arguably comparable to a stack of testosterone and winstrol. Again, SARMS are not steroids, and they provide less androgenic and anabolic effects as actual steroids, but the effects are very similar. Andarine can also be used by itself and provide fantastic results.
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