Wuhan Biofriend Technology Co.,Ltd

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High Purity Avanafil 330784-47-9 Raw Steroid Powders For Steroid Hormone

Good quality Injectable Anabolic Steroids for sales
Good quality Injectable Anabolic Steroids for sales
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High Purity Avanafil 330784-47-9 Raw Steroid Powders For Steroid Hormone

China High Purity Avanafil 330784-47-9 Raw Steroid Powders For Steroid Hormone supplier
High Purity Avanafil 330784-47-9 Raw Steroid Powders For Steroid Hormone supplier High Purity Avanafil 330784-47-9 Raw Steroid Powders For Steroid Hormone supplier High Purity Avanafil 330784-47-9 Raw Steroid Powders For Steroid Hormone supplier High Purity Avanafil 330784-47-9 Raw Steroid Powders For Steroid Hormone supplier

Large Image :  High Purity Avanafil 330784-47-9 Raw Steroid Powders For Steroid Hormone

Product Details:

Place of Origin: Wuhan
Brand Name: Biofriend
Certification: SGS,ISO9001,UKAS,GMP
Model Number: 330784-47-9

Payment & Shipping Terms:

Minimum Order Quantity: 10g
Price: Negotiable
Packaging Details: Discreet ways of packing for customs guaranteed
Delivery Time: Within 8 hours after payment
Payment Terms: T/T, Western Union, MoneyGram,Bitcoin,Paypal
Supply Ability: 2000kg Per Month
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Detailed Product Description
Name: Avanafil CAS: 330784-47-9
MF: C23H26ClN7O3 MW: 483.9506
Character: White To Off-White Cyrstalline Powder Usage: Steroid Hormone

Safety and High Purity Avanafil 330784-47-9 Sex Enhancing Drugs Steroid Hormone Powder
 

1. Product Details:

 

Synonyms: (S)-2-(2-Hydroxymethyl-1-pyrrolidinyl)-4-(3-chloro-4-methoxybenzylamino)-5-[(2-pyrimidinylmethyl)carbamoyl]pyrimidine;4-[(3-Chloro-4-methoxybenzyl)amino]-2-[2-(hydroxymethyl)-1-pyrrolidinyl]-N-(2-pyrimidinylmethyl)-5-pyrimidinecarboxamide;Avanafil;Avanafil (usan/inn);D03217;4-[[(3-Chloro-4-Methoxyphenyl)Methyl] aMino]-2-[(2S)-2-(hydroxyMethyl)-1-pyrrolidinyl]-N-(2-pyriMidinylMethyl)-5-pyriMidinecarboxaMide;4-((3-chloro-4-Methoxybenzyl)aMino)-2-(2-(hydroxyMethyl)pyrrolidin-1-yl)-N-(pyriMidin-2-ylMethyl)pyriMidine-5-carboxaMide;(S)-4-((3-Chloro-4-Methoxybenzyl)aMino)-2-(2-(hydroxyMethyl)pyrrolidin-1-yl)-N-(pyriMidin-2-ylMethyl)pyriMidine-5-carboxaMide

Assay: 99% min.

CAS: 330784-47-9

Molecular Formula:C23H26ClN7O3
Molecular Weight:483.9506
Character: White to Off-White Cyrstalline Powder

Usage: Used for the treatment of erectile dysfunction. A phosphodiesterase 5 inhibitor.

Categories: Active Pharmaceutical Ingredients; Cnbio; Erectile Dysfunction; Inhibitors; Intermediates & Fine Chemicals; Pharmaceuticals; API's.

Certificates:SGS,ISO 9001, GMP

MOQ:10 gram

Provide Samples: Yes.

Delivery time: Within 12 hours upon receipt of payment

Payment method: T/T,western union, money gram, bitcoins, bank transfer

Skype: steroidlab

Price: Factory price(Negociable)
Packing: Discreet and Disguised packing to pass the customs.
Delivery methods: EMS, DHL, TNT, FedEx, UPS,etc door to door.

Standard: GMP Enterprise standard.

The min. order is 10 grams.

Export Markets:Global

Storage: Shading, Confined Preservation
Usage:Used for the treatment of erectile dysfunction. A phosphodiesterase 5 inhibitor

 

2. Description:

 

Avanafil is a highly selective PDE5 inhibitor with IC50 of 1 nM.
Avanafil is a PDE5 inhibitor approved for erectile dysfunction by the FDA on April 27, 2012 [1] and by EMA on June 21, 2013.[2] Avanafil is known by the trademark names and was developed by Vivus Inc. In July 2013 Vivus announced partnership with Menarini Group, which will commercialise and promote in over 40 European countries plus Australia and New Zealand.[3] Avanafil acts by inhibiting a specific phosphodiesterase type 5 enzyme which is found in various body tissues, but primarily in the corpus cavernosum penis, as well as the retina.Other similar drugs are tadalafil and vardenafil.

 

3. Usage:
It is a development of the phosphodiesterase type 5 inhibitors, for the treatment of male sexual dysfunction, at present in the America, EU and Japan have completed phase II clinical trials, phase III clinical trials will start. The product is composed of Japanese Tanabe Pharma Company and VIVUS company development. In addition to oral dosage forms, VIVUS company is also developing Avanafil urethral administration, for not responding to oral dosage forms of patients.

Avanafil is a potent, highly selective phosphodiesterase 5 inhibitor, in vitro experiments showed that the selectivity of phosphodiesterase 5 stronger than . The compound dear compliance weak against other phosphodiesterase, and effect of adenosine receptor decreased, suggesting that the cardiovascular effects of avanafil should be weaker than .

Pre clinical study showed that avanafil and organic nitrate drugs taken in combination to reduce its on blood pressure was significantly weaker than and nitrate drugs with clothes. Moreover, avanafil inhibition of phosphodiesterase 6 is very weak, the relevant visual disturbance suppression may the enzyme phosphodiesterase 5 inhibitor induced and other.

 

4. COA

 

Test Items Specification Test Results
Description White or almost white crystalline powder White crystalline powder
Melting Point 191.0~193.0ºC 192ºC
Loss of drying ≤1.0% 0.5%
Heavy Metal ≤20ppm 15ppm
TLC Only one spot Only one spot
Assay ≥99.5% 99.91%

 

5. Application:

 

The advantage of avanafil is that it has very fast onset of action compared with other PDE5 inhibitors. It is absorbed quickly, reaching a maximum concentration in about 30-45 minutes.About two-thirds of the participants were able to engage in sexual activity within 15 minutes.

 

High Purity Avanafil 330784-47-9 Raw Steroid Powders For Steroid Hormone

 

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7.Recommended products (Injection Liquid)

 

 

Product Name (Intramuscular injection)

 

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Cypoject 250 (Testosterone Cypionate)

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Enanject 250 (Testosterone Enanthate)

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Enanject 600 (Testosterone Enanthate)

600mg/ml

 

Propionat 100 (Testosterone Propionate)

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Propionat 200 (Testosterone Propionate)

200mg/ml

 

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Sustanon 250

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Sustanon 300

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Sustanon 400

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Boldenone 300 (Boldenone undecylenate)

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Boldenone 200 (Boldenone Cypionate)

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Nandrolone 200 (Nandrolone Cypionate)

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NPP 200

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Deca 250

250mg/ml

 

Deca 200

200mg/ml

And more



6.Packaging&Delivery
1).We promise to provide high purity of raw steroid powders & semi-finished liquid;

2).We have professional packing team always find new ways to make the disguised package for custom pass guaranteed;

3).We have Long term cooperation Express courier companies to delivery your goods safe and speedy door to door;

4).We always thinking more for customers, 24/7 good after-sale service to solve the problems at any time;

5).Resend policy once the parcel delivery failed by accident.

Contact Details
Wuhan Biofriend Technology Co.,Ltd

Contact Person: Jelly

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