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Tasimelteon Hetlioz Sleep Disorder Medicine Pharma Raw Materials CAS 609799-22-6

China Tasimelteon Hetlioz Sleep Disorder Medicine Pharma Raw Materials CAS 609799-22-6 supplier
Tasimelteon Hetlioz Sleep Disorder Medicine Pharma Raw Materials CAS 609799-22-6 supplier Tasimelteon Hetlioz Sleep Disorder Medicine Pharma Raw Materials CAS 609799-22-6 supplier

Large Image :  Tasimelteon Hetlioz Sleep Disorder Medicine Pharma Raw Materials CAS 609799-22-6

Product Details:

Place of Origin: China
Brand Name: Biofriend
Certification: ISO9001
Model Number: 609799-22-6

Payment & Shipping Terms:

Minimum Order Quantity: 10g
Price: USD1-10/g
Packaging Details: stealth package
Delivery Time: 5-8 works day
Payment Terms: T/T, Western Union, MoneyGram,Bitcoin
Supply Ability: 5000kg
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Detailed Product Description
Color: White Appearance: Powder
Product Name: Tasimelteon Assay: 99%
Alias: Hetlioz Usage: Sleep Disorder
Cas: 609799-22-6

Tasimelteon Hetlioz Sleep Disorder Medicine Pharma Raw Materials CAS 609799-22-6

 

Specification:

 

Product Name:Tasimelteon
Alias:Hetlioz
CAS NO.:609799-22-6
Molecular Formula:C15H19NO2
Molecular Weight:245.32
Purity:99%
Appearance:White Powder
Grade:Pharmaceutical Grade

Tasimelteon Hetlioz Sleep Disorder Medicine Pharma Raw Materials CAS 609799-22-6

 

Description:

 

Tasimelteon is a melatonin receptor agonist. Because of the high density of melatonin receptors

 

in the circadian pacemaker, the suprachiasmatic nucleus, melatonergic actions can phase-shift

 

circadian rhythms and promote sleep. Tasimelteon was effective in reducing sleep onset latency

 

(in phase II and III clinical trials) and in resetting the circadian melatonin rhythm (in phase II trials),

 

which indicated its potential suitability as treatment for jet lag, shift work and circadian rhythm

 

sleep disorders. Statistically significant improvements in sleep maintenance have also been

 

observed with the drug. Tasimelteon has been claimed to be useful in the treatment of

 

depression, and preclinical evidence in this respect is to be confirmed in a phase II clinical trial,

 

which was ready to be initiated at the time of publication. It is plausible that the drug may be

 

effective in the treatment of depressive disorders, at least those that are related to circadian

 

dysfunction, and that it may attenuate sleep problems in depressed patients of different subtypes.

 

A general suitability in mitigating other symptoms of major depressive disorder cannot be

 

deduced from the actions of tasimelteon via the melatonin receptors MT1 and MT2. The drug is

 

well tolerated, does not induce impairment of next-day functioning or dependence, and seems to

 

be safe in short-term treatment; however, toxicological data would be required for assessing its

 

long-term safety.

 

 

Effects

 

Tasimelteon is a melatonin receptor agonist. It works by targeting receptors in the brain that control the timing of the sleep-wake cycle. In clinical trials, totally blind individuals with Non-24 who were treated with tasimelteon slept longer during the night. Tasimelteon was also found to decrease the amount of time totally blind individuals with Non-24 slept during the day.
Tasimelteon is a selective agonist for the melatonin receptors MT1 and MT2, similar to other members of the melatonin receptor agonist class of which ramelteon (2005) and agomelatine (2009) were the first approved.As a treatment for N24HSWD, as with melatonin or other melatonin derivatives, the patient may experience improved sleep timing while taking the drug. Reversion to baseline sleep performance occurs within a month of discontinuation.
Tasimelteon Hetlioz Sleep Disorder Medicine Pharma Raw Materials CAS 609799-22-6
 

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