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Top Quality Antidepressant Use Tianeptine Sodium Pharmaceutical Raw Powder Cas 30123-17-2

China Top Quality Antidepressant Use Tianeptine Sodium Pharmaceutical Raw Powder Cas 30123-17-2 supplier
Top Quality Antidepressant Use Tianeptine Sodium Pharmaceutical Raw Powder Cas 30123-17-2 supplier Top Quality Antidepressant Use Tianeptine Sodium Pharmaceutical Raw Powder Cas 30123-17-2 supplier

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Product Details:

Place of Origin: China
Brand Name: Biofriend
Certification: ISO9001
Model Number: 30123-17-2

Payment & Shipping Terms:

Minimum Order Quantity: 10g
Price: USD1-10/g
Packaging Details: stealth package
Delivery Time: 5-8 works day
Payment Terms: T/T, Western Union, MoneyGram,Bitcoin
Supply Ability: 5000kg
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Detailed Product Description
Color: White Appearance: Powder
Product Name: Tianeptine Sodium Cas: 30123-17-2
Assay: 99% Usage: Antidepressant

Top Quality Antidepressant Use Tianeptine Sodium Pharmaceutical Raw Powder Cas 30123-17-2

 

 

Basic Info.

 

Product name: Tianeptine Sodium Salt
Assay: 99%
CAS No: 30123-17-2
Packing Customized: package as you require
M.F.: C21H24ClN2NaO4S
M.W.: 458.93
Appearance: White crystalline powder
Quality Standard: Enterprise Standard
Usage: Treatment of depression.

 

 

Description:


Tianeptine sodium is primarily used for its mood boosting and anti-anxiety properties. This substance also has nootropic abilities in regards to individuals whose cognition is negatively impacted by mood disorders. It has the ability to improve focus and concentration in individuals who have poor attention spans as well.
Depressive illness devastates millions of lives. Tianeptine is a neuroprotective antidepressant that reverses the neuronal damage and lasting misery caused by chronic, uncontrolled stress. Tianeptine acts both as a non-sedating anti-anxiety agent and a non-stimulating mood-brightener. Uniquely in clinical medicine, tianeptine acts as a selective serotonin reuptake enhancer. Its puzzling efficacy as an antidepressant illustrates how little modern psychiatric medicine really understands about mind, mood and depression.
Tianeptine is chemically a tricyclic antidepressant (TCA), but it has different pharmacological properties than typical TCAs as recent research suggests that tianeptine produces its antidepressant effects through indirect alteration of glutamate receptor activity (i.e., AMPA receptors and NMDA receptors) and release of BDNF, in turn affecting neural plasticity.

 

Application:

 

Tianeptine shows efficacy against serious depressive episodes (major depression), comparable to amitriptyline, imipramine and fluoxetine, but with significantly fewer side effects. It was shown to be more effective than maprotiline in a group of people with co-existing depression and anxiety. Tianeptine also displays significant anxiolytic properties and is useful in treating a spectrum of anxiety disorders including panic disorder, as evidenced by a study in which those administered 35% CO2 gas (carbogen) on paroxetine or tianeptine therapy showed equivalent panic-blocking effects. Like many antidepressants (including bupropion, the selective serotonin reuptake inhibitors, the serotonin-norepinephrine reuptake inhibitors, moclobemide and numerous others) it may also have a beneficial effect on cognition in people with depression-induced cognitive dysfunction.

Tianeptine sodium salt is a drug used primarily in the treatment of major depressive disorder, although it may also be used to treat asthma or irritable bowel syndrome. Chemically it is a tricyclic antidepressant (TCA), but it has different pharmacological properties than typical TCAs as recent research suggests that tianeptine produces its antidepressant effects through indirect alteration of glutamate receptor activity (i.e., AMPA receptors and NMDA receptors) and release of BDNF, in turn affecting neural plasticity.
Tianeptine has antidepressant and anxiolytic (anti-anxiety) properties with a relative lack of sedative, anticholinergic and cardiovascular adverse effects, thus suggesting it is particularly suitable for use in the elderly and in those following alcohol withdrawal; such persons can be more sensitive to the adverse effects of psychotropic drugs. Recent results indicate possible anticonvulsant (anti-seizure) and analgesic (painkilling) activity of tianeptine via immediate or downstream modulation of adenosine A1 receptors (as the effects could be experimentally blocked by antagonists of this receptor).

 

Specification:

 

Tests Specifications Results
Description White to yellowish powder, very hygroscopic. Off-white powder, very hygroscopic.
Solubility Freetly soluble In water and methanol and dichloromethane Complies
Identification (1)By IR, To match with working standard Complies
(2)It gives reaction of sodium Complies
Impurities A ≤0.1% Not detected
Related compounds Any impurity ≤0.1% <0.1%
Total impurities ≤0.4% 0.25%
Residual Solvents Acetidin≤ 0.5% Not detected
Dichloromethane≤ 0.06% Not detected
Methanol≤ 0.3% Not detected
Acetone ≤ 0.5% Not detected
Acetonitrile≤0.041% Not detected
Ethanol≤0.5% 0.04%
N, N-dimethylformamide≤0.088% Not detected
Water ≤ 5.0% 1.38%
Assay 99.0%-101.0%(On anhydrous basis) 99.98%
Conclusion Conform to EP8.0

 

Top Quality Antidepressant Use Tianeptine Sodium Pharmaceutical Raw Powder Cas 30123-17-2

Excretion

Tianeptine Sulfate is excreted much more slowly than Tianeptine Sodium, meaning it remains active within the body for a longer duration.

 

Hygroscopicity

One of the main downsides to Tianepine Sodium is its ability to clump after exposure to normal conditions.
Tianeptine Sulfate does not absorb moisture from the air, and remains as a powder - making it much easier to work with.


Stability

Tianeptine Sodium is not stable in atmospheric moisture, and is very light sensitive, degrading quickly when exposed. Tianeptine Sulfate is much more stable, with much less light degradation.

Taste:
The taste of Tianeptine Sodium has been described as "bitter" and reportedly "tastes like death".
Tianeptins Sulfate, on the other hand, has very little taste at all.

 

Funstion

Improving Memory


mproving the brain function


Preventing and treating senile dementia


Enhancing the learning ability


Increasing the attention


Relieving the anxiety

Tianeptine sulphate is an improved salt of Tianeptine.

It is not hygroscopic so handling the powder is a lot easier. Since it is not as readily absorbed and excreted from the body, the sulfate salt allows for a more controlled release of the Tianeptine over longer periods. Rather than having to dose three times with rapid peak effects and rapidly falling effects, the sulfate salt allows for one dose to maintain plasma levels in the body much longer than the sodium salt. These improved characteristics make Tianeptine Sulfate a novel addition.


Longer lasting
Based on chemical structure and recent online reviews, the Sulphate form of Tianeptine has a

Longer duration.
This is caused, in part, by a slower rate of absorption.

More stability
Unlike Tianeptine Sodium, the Sulphate form is not hygroscopic, meaning itdoes not absorb moisture from the air.
Furthermore, it is more stable when exposed to light.

Preferred
From the preliminary online discussions, Tianeptine Sulphate is preferred among users.
It is likely to replace Tianeptine Sodium in time, due to favorable pharmacodynamics.

Top Quality Antidepressant Use Tianeptine Sodium Pharmaceutical Raw Powder Cas 30123-17-2

 

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