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Trenbolone White Powder Tibolone Livial CAS 5630-53-5 Purity 99.5% for Treatment Breast Cancer
Tibolone is structurally related to 19-nortestosterone derivatives and is a new postmenopausal regimen with a unique pharmacological profile, licensed for the relief of climacteric symptoms and the prevention of osteoporosis in postmenopausal women.
1. Quick Details:
|Other name :||Winstrol; Androstanazole; Stromba; Winstrol Depot; Androstanazol; Stanazolol; Strombaject; Estazol; Tevabolin|
|Packing:||foil bag or tin|
|Character:||White crystalline powder.|
|Categories:||Pharmaceutical; Active Pharmaceutical Ingredients; Biochemistry; Steroids|
2. Tibolone Description and Indication:
Tibolone is a synthetic hormone-type drug which is used mainly for hormone replacement therapy in post-menopausal women. It is a synthetic steroid that has the same activity as the female sex hormones estrogen and progesterone and the androgen testosterone. Tibolone helps restore hormonal balance in the body.
When estrogen levels are low tissues can slowly degenerate, as is experienced during menopause. In addition, low levels of estrogen can cause distressing symptoms such as hot flushes, night sweats, mood swings, reduced sex drive and vaginal dryness.
Tibolone is broken down into three compounds which act in a similar way to the natural estrogen and progesterone found in the body. It restores plasma endorphin level in post-menopausal women and acts centrally to affect the thermo-regulatory system.
In itself Tibolon has no biological activity; the effects are produced mainly by the results of the activity of its metabolites on various tissues. After administration, it is quickly metabolized into 3α-hydroxytibolon and 3ß-hydroxytibolon compounds, which are also present in an inactive, sulfated form. A third compound, the Δ4- isomer is formed from Tibolon directly or from the 3ß hydroxymetabolite.
Tibolon has estrogenic effects on bone and vaginal tissue. The Δ4-isomer functions as a progestogen in endometrial tissue, whereas in the brain and liver it has androgenic effects.In breast tissue, Tibolon acts by strongly inhibiting sulfate activity and weak inhibition of 17α-hydroxysteroid dehydrogenase activity, which results in blocking the conversion of estrone sulfate to E2.
Tibolon Contraindications;Tibolon is contraindicated in patients with the following conditions:,Women with hormone treated tumors,Undiagnosed vaginal bleeding,Pregnancy/lactation,Liver and/or cardiac disease,Tibolon Adverse Drug Effects,Depression,Diarrhea, constipation, nausea, vomiting or abdominal pain,Visual disturbances,Alteration in results of liver function tests,Excessive fluid retention in the body tissues resulting in swelling (edema),weight changes, vaginal bleeding, pain in the muscles and joints, rashes or itching,Seborrhoeic dermatitis,Headaches, dizziness, growth of facial hair.
4. How to Use Tibolone:
Follow carefully instructions of use of tibolone provided from your doctor. Consult your doctor or pharmacist when in doubt. Follow the instructions of the physician in preference to those given in this website, which may be different. Ask your doctor to explain any aspect that you do not understand, contained in the instruction leaflet that comes with the medicine.
Tibolone should not be taken until two months after the last natural menstruation. If taken before, may be increased the possibility of having an irregular vaginal bleeding.
Taking tibolone for the first time
- If you have not taken any other drug for hormone replacement therapy before, you can start immediately.
If you switch from another preparation for hormone replacement therapy:
There are several types of medicines such as tablets, patches, or gels. With some of them, you may have bleeding between cycles (sequential) and others are taken continuously.If you were taking a sequential medicine, you should start taking tibolone immediately after the end of bleeding. If you were taking a continuous medicine (no bleeding) you may also start taking it at any time.
Tibolone should be taken orally. Take one tablet every day, which can be swallowed with some water or other drink.
Take the tablets at the same time each day. The blisters (containing each one a tablet) are marked with the corresponding day of the week.Start by taking the tablet marked with the correspondent day of the week. For example, if it's Monday, take the tablet marked Monday on the upper row of the blister. Follow the arrows until the blisters are empty. Start the next strip the next day. Do not leave any day between blisters or boxes.
Relief of menopausal symptoms generally occurs during the first weeks of treatment, and optimal results are obtained if the treatment continues for at least 3 months.If you think the effect of the medicine is too strong or too weak, consult your doctor.
If you have any further questions on the use of this product, ask your doctor or pharmacist.
5. Take Special Care with Tibolone:
Before starting tibolone treatment, you should inform your doctor about your personal and family medical history. Your doctor will perform a thorough physical and gynecological examination before beginning treatment and periodically along its duration, especially breast.
Should see your doctor immediately if any of these conditions worse or appear while taking tibolone:
- Gynecological disorders of any kind
- Changes or alterations in the breast
- High levels of fat (triglycerides) in the blood or a family history of this
- Hypertension, particularly if it worsens or does not improve with antihypertensive therapy
- Disorders of the liver or kidney
- Functional disorders of the gallbladder
- Headaches (migraines) intense and repetitive
- An immune disease called systemic lupus erythematosus
- Jaundice (yellowing of the skin and whites of the eyes)
- Pruritus (itching)
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