CAS 224785-91-5 Vardenafil
Alias: Levitra; Fardenafil,Vardenafil hydrochloride
Molecular Formula: C23H32N6O4S
CAS No: 224785-91-5
Grade: Pharmaceutical Grade
Appearance: White to almost white crystalline powder
Vardenafil is used for:
Treating erectile dysfunction (ED). It may also be used for other conditions as determined by your doctor.
Vardenafil is a phosphodiesterase type 5 (PDE5) inhibitor. It works by helping to increase blood flow into the penis during sexual stimulation. This helps you to achieve and maintain an erection.
Vardenafil is a PDE5 inhibitor used for treating erectile dysfunction. Vardenafil's indications and contra-indications are the same as with other PDE5 inhibitors; it is closely related in function to Sildenafil citrate (Viagra) and Tadalafil (Cialis). The difference between the Vardenafil molecule and Sildenafil citrate is that a nitrogen atom has different position and the change of Sildenafil's piperazine ring methyl group to an ethyl group. Tadalafil is structurally different from both Sildenafil and Vardenafil. Vardenafil's relatively short effective time is comparable to but somewhat longer than Sildenafil's.
Further, Vardenafil lengthens QT interval. Therefore it should not be taken by men taking other medications that affect the QT interval (such as Amiodarone).
Vardenafil Side Effects
Facial flushing (reddening), headaches, stomach upset, diarrhea, flu like symptoms and nausea. Vardenafil also may cause chest pain, low blood pressure, blurred vision and changes in color vision, abnormal ejaculation and priapism (painful erection).
Patients taking Levitra are usually started on a 10 mg dose, which they take no more than once daily, about one hour before sexual activity. It can take as little as 30 minutes for Levitra to work in some patients. Like with Viagra, Levitra dosages are adjusted depending on a person's reaction, with doctors generally decreasing doses to to 2.5 mg or increasing them to no more than 20 mg once a day.
Vardenafil, as with all PDE5 inhibitors, should not be used by men taking nitrate medications, because combining them with Vardenafil might provoke potentially life-threatening hypotension (low blood pressure).