Clomid is a drug given to women for use as a fertility aid. Clomid, however, is much weaker than Nolvadex in a mg for mg comparison, with roughly 150mgs of Clomid being equal to 20mgs of Nolvadex (1). It should be noted, however, that 150mgs of Clomid will still raise to approximately 150% of baseline value(1). You don´t have to use 150mgs, however; In my research, I´ve found that doses as low as 50mgs will show improvements and elevations In fact, my original Post-Cycle-Therapy regime (as suggested by Dan Duchaine in the original Underground Steroid Handbook) was 100mgs per day for a week and 50mgs/day for a week. Don´t laugh& for the late 90´s, when most anabolic steroid users didn´t even know how to use Clomid, it was considered a "state of the art" PCT routine. I suspect that Duchaine originally introduced this compound to the steroid using community.
Clomid, just like Nolvadex, is very safe for long term treatment of lowered with some studies showing its safety and efficacy for up to four months. And post-cycle, when steroid users are suffering form lowered , is when Clomid is most effective.
Clomiphene Citrate is a SERM that is specifically used as a fertility aid due to its ability to enhance the release of gonadotropins. Clomid has the ability to oppose the negative feedback of estrogens on the Hypothalamic-Pituitary-Ovarian-Axis. This will increase the release of Luteinizing Hormone (LH) and Follicle Stimulating Hormone (FSH) significantly. By increasing gonadotropin release, this can lead to the egg being released, thereby increasing the chance of conception.
Clomid also carries strong anti-estrogen properties that could be used therapeutically, but its anti-estrogen properties are most commonly associated with anabolic steroid use. Testosterone and many Testosterone derived steroids have the ability to convert to estrogen through Testo-ster-one's interaction with the aromatase enzyme. As estrogen levels rise, this can lead to gynecomastia and excess water retention. Heavy water retention can also promote high blood pressure. By supplementing with Clomid during anabolic steroid use, the SERM will bind to the estrogen receptors, therefore inhibiting the estrogen hormone from binding. This can be very useful in combating gynecomastia, as when Clomid binds to the receptor it prevents estrogen from stimulating the mammary tissue. It can also have a positive impact on water retention, but as it won't actively reduce serum estrogen levels it's sometimes not enough.
Clomid also possess functioning traits that are beneficial to the anabolic steroid user post anabolic steroid use. Specifically we're referring to Post Cycle Therapy (PCT). In men, Clomid also has the ability to stimulate the pituitary to release more LH and FSH, which will in turn stimulate enhanced natural Testosterone production. This is extremely beneficial to the anabolic steroid user post cycle as natural Testosterone levels will be very low due to suppression caused by anabolic steroid use.
Clomid was one of the original drugs used in post-cycle-therapy to stave off gynocomastia and raise the body's natural testosterone levels. There are some side effects involved with heavy prolonged use, such as vision problems, and there are more effective substances on the market that do the same thing, but Clomid is still an effective and inexpensive compound for any athlete's post-cycle-therapy.
For athletic purposes, Clomid does not offer a tremendous benefit to women. In men however, the elevation in both follicle stimulating hormone and (primarily) luteinizing hormone will cause natural testosterone production to increase.
Male bodybuilders who cycle anabolic androgenic steroids (AAS) have found that the same mechanisms of increased LH (luteinizing hormone) can be taken advantage of to increase total testosterone levels. This is why clomid is popular in post cycle therapy (PCT) among those who cycle anabolic steroids.
Since clomid has ability to bind to the estrogen receptors, much like nolvadex, in male users who run estrogenic compounds such as , dianabol, and deca durabolin, it can be used as gynecomastia treatment (anti-gyno).
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