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Prodcut name: Spironolactone
Synonym: Aldactone;Antisterone;spirolactone;7-alpha-Acetylthio-3-oxo-17-alpha-pregn-4-ene-21,17-beta- carbolactone
CAS Registry Number: 52-01-7
Packaging: 1kg/foil bag
Molecular Formula: C24H32O4S
Molecular Weight: 416.5735
Appearance: White or almost white fine crystalline powder;Slightly bitter taste, odourless or slightly mercaptan odor.Insoluble in water, soluble in ethanol, soluble in benzene or ethyl acetate.
Usage: Spironolactone is competitive inhibition of aldosterone drugs, drug itself is not active, role is diuresis and endogenous competitive aldosterone antagonist and happen, belongs to the potassium diuretics.
It is a synthetic, steroidal antimineralocorticoid and antiandrogen that also has some weak progestogen properties, as well as some indirect estrogen and glucocorticoid effects. It is used primarily as a diuretic and antihypertensive, but may also be employed for the purpose of reducing elevated or unwanted androgen activity in the body.It acts predominantly as an antagonist of the mineralocorticoid (or aldosterone) and androgen receptors, and in relation to its antimineralocorticoid effects, belongs to a class of pharmaceutical drugs known as potassium-sparing diuretics.
Spironolactone (CAS: 52-01-7):
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