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Anti Estrogen Steroids Tamoxifen Citrate / TCT / Nolvadex for Burning Fat CAS 54965-24-1

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Anti Estrogen Steroids Tamoxifen Citrate / TCT / Nolvadex for Burning Fat CAS 54965-24-1

China Anti Estrogen Steroids Tamoxifen Citrate / TCT / Nolvadex for Burning Fat CAS 54965-24-1 supplier
Anti Estrogen Steroids Tamoxifen Citrate / TCT / Nolvadex for Burning Fat CAS 54965-24-1 supplier Anti Estrogen Steroids Tamoxifen Citrate / TCT / Nolvadex for Burning Fat CAS 54965-24-1 supplier

Large Image :  Anti Estrogen Steroids Tamoxifen Citrate / TCT / Nolvadex for Burning Fat CAS 54965-24-1

Product Details:

Place of Origin: China
Brand Name: Biofriend
Certification: ISO9001
Model Number: 54965-24-1

Payment & Shipping Terms:

Minimum Order Quantity: 10g
Price: USD1-10/g
Packaging Details: stealth package
Delivery Time: 5-8 works day
Payment Terms: T/T, Western Union, MoneyGram,Bitcoin
Supply Ability: 5000kg
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Detailed Product Description
Color: White Appearance: Powder
Skype: Hopec95817

 
Please kindly contact us to know more
Contact Hope Whatsapp: +86-18164245853 Email : hope@chembj.com

 

Anti Estrogen Steroids Tamoxifen Citrate / TCT / Nolvadex for Burning Fat CAS 54965-24-1

 

Application

 

For the treatment of advanced and recurrent breast cancer and ovarian cancer, etc.

1. Treatment of breast cancer.
2. Prevention of breast cancer.
3. Anti-tumor and anti-multidrug resistance.
By reducing membrane negotiability and enhancing rigidity of inter-cell binding site, Tamoxifen citrate can reduce concentration and activity of cancer metastasis promoter and various activating enzymes, so as to inhibit or hinder growth and metastasis of cancer cell. In addition, it can promote cells surrounding tumor focus to secrete a negative growth factor-transforming growth factor TGF-G, inhibiting multiply indefinitely of cancer cells; inhibiting oxidative damage of DNA bases which is caused by hydrogen peroxide generated from human neutrophils. So except for breast cancer, it is good for treatment and prevention of other malignant neoplasms, and is used for treatment of brain tumors, liver cancer, prostate cancer, etc. In addition, Tamoxifen citrate can reduce release effect of membrane P170 glycoprotein through reducing membrane negotiability, improving intracellular effective concentration of cytotoxic drug and reducing drug resistance.
4. Heart protection.
The above information is edited by the Chemicalbook of Liu Yujie.

 

Side effects

 

Common slight side effects includes nausea, vomiting and facial flushing etc.

 

Description

 

Tamoxifen citrate(Tamoxifen, abbreviation TCT ), is an estrogen competitive antagonist and non-steroidal anti-estrogen drug. It can compete with estrogen (estradiol) to combine with estrogen receptor of breast cancer cells, inhibiting the effect of estrogen on cancer cells, and stunting growth and development of tumor cells to show anticancer effects. Clinically Tamoxifen citrate is commonly used to treat various types of breast cancer, especially for postmenopausal breast cancer women with the positive of estrogen receptor and progesterone receptor and with low prostate-specific antigen levels.

 

Mechanism of action

 

TCT has cis-trans isomers, whose cis isomer shows a weak estrogenic effect, while the trans isomer has an anti-estrogenic effect. When early application of Tamoxifen or existence of low concentration, it binds to the estrogen receptor (ER) in cytoplasm, showing a weak estrogenic effect. After TCT entering into cell nucleus, it can inhibit transcription and synthesis of nuclear ER, generating a lasting anti-estrogen effect. The study found that many new features of TCT were related to the mechanism of action which was beyond its competitive estrogen receptors-membrane regulating mechanisms. TCT as the membrane modifier, can reduce cell circulation. On this basis, TCT can also serve as an antioxidant to protect cell membranes and human LDL from happening oxidative damage.

 

Pharmacodynamics

 

The oral absorption of TCT is slow, plasma concentration reaches peak at 3 to 6 hours. After absorbed in the liver, Tamoxifen citrate is metabolized into N-demethyl tamoxifen whose activity is similar to Tamoxifen citrate. The half-life of Tamoxifen citrate is 5 to 7 days, and its metabolite N-demethyl tamoxifen is 7 to 14 days. Animal experiments show that tamoxifen citrate and N-demethyl tamoxifen cycle in extensive enterohepatic. As for single oral dose of TCT 20mg, its peak of plasma concentration is approximately 40 ng/ml (range; 67~183ng/ml) and 336ng ml (range: 148~654ng/ml). Steady-state plasma concentration of tamoxifen citrate is needed continuous administration for 3 to 4 weeks, and N-demethyl tamoxifen is generally needed continuous administration for 3 to 8 weeks. Tamoxifen citrate and most other metabolites are mainly excreted in feces, small part metabolites are excreted in the urine.

 

 

 

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Anti Estrogen Steroids Tamoxifen Citrate / TCT / Nolvadex for Burning Fat CAS 54965-24-1
1. WHAT services do you offer?
We can offer the Custom premixes, Semi-Finished products, raw steroid hormone powder.We can also assist with formulations, blends and custom packing. We are your complete source for today and tomorrow's most potent and popular natural ingredients. With experience of more than 500 formula products, if you can envision a functional product, we can make it happen.
2. HOW do I make an order?
Simply contact us by telephone or email.We will connect you with one of our managers who will be happy to assist you with your order.Rip Cut 175 Mg/Ml Homebrew Injectable Oil Rip Cut 175
3. WHEN will my order ship?
Products in stock usually ship within 24hours of your order being received and processed. If a product is not in stock, turnaround time varies but is generally about 1-3 weeks, depending on availability.
4. DO you sell small quantities to end users?
We accept any quantity for order, from grams to tons.
5. DO you Identity Test your Products?
Yes, we test the ID for all incoming raw materials before production of the extracts in the country of origin. Testing ID before any processing takes place helps us to deliver you the highest quality ingredients at the lowest possible prices.Rip Cut 175 Mg/Ml Homebrew Injectable Oil Rip Cut 175
Steroids Order Processing

Items Content
Make an order State what kind of steroids and quantity for each powder you want
Shipping Provide your addressee info ( phone number )
Packing Chosen according to your country and quantity of order
Delivery Arranged within 12 hours upon receipt of your payment
Photos Photos of parcel would be offered to tell apart the steroids .
Tracking number Offered once it is released
After-sale service 24/7 online for your all kinds of steroids powder problems

Our advantage:
1,We only send the HIGHEST purity Steroids, Peptides, Research chemicals & Pharmaceuticals which are very popular in many countries like Kazakhstan ,Poland,Hungary ,Paraguay ,Uruguay,Brazil, Russia, Portugal, Latvia, Switzerland, Iceland, Ukraine, Germany, France, Netherlands, Belgium,Peru, Sweden, New Zealand, the Czech Republic, Lithuania, Ireland, Tunisia, Mexico, Greece, Puerto Rico, Serbia,Finland ,Italy , Estonia ,Thailand, Israel ,US, UK, Canada, Australia
2,Our prices are the best because of the discounts that we give to all our buyers. We give very good discounts which makes our prices outstanding in the market.
3,Genuine and 100% Guarantee on all orders you place. We Have the Best you will come across Online. We have adequate stock, and can arrange the delivery within 24hours when receiving the payment. Tracking number would be informed quickly after shipment.
4,We have the best customer service and excellent shipment ability. Contact us to have a full list of our products and price list.
5,Besides raw steroid powder and liquid,we offer hormone solution and formula.We can teach you how to make hormone solution on the site. Any visit to our lab is welcomed.

Anti Estrogen Steroids Tamoxifen Citrate / TCT / Nolvadex for Burning Fat CAS 54965-24-1
 

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