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|Product Name:||Hydrochloride||Synonyms:||D- Hydrochloride; DL- Hydrochloride|
|Assay:||99% Min||Appearance:||White Powder|
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High Effective Sex Enhancement Drugs White Powders Hydrochloride 129938-20-1
1) Hydrochloride Details
|Synonyms||d- hydrochloride; DL- hydrochloride|
|Standard||USP/ Enterprise Standard|
|Chemical Properties||White to Off-White Cyrstalline Solid, odorless, slight sweet taste, MP 175-177℃, optical rotation +128°|
hydrochloride is a short-acting novel selective serotonin reuptake inhibitor marketed for the treatment of premature ejaculation in men.Premature
ejaculation (PE) is the most common male sexual disorder, estimated to affect up to 30% of men.
|Packing||1kg net/foil bag, 25kg/drum|
2) Hydrochloride Features
() as a new fast SSRI, a short half life, a selective 5 - HT reuptake inhibitor (SSRI),
for the treatment of premature ejaculation and erectile dysfunction. is a selective 5-HT reuptake inhibitor (SSRI), such drugs widely used to treat depression and related affective disorders.
Treat male premature ejaculation and erectile dysfunction. , on the other hand, is a fast-acting SSRI. It is rapidly absorbed and eliminated from the body within a few hours. This favorable pharmacokinetics minimizes the risk of the drug’s accumulation in the body, and therefore reducing side effects.
3) Hydrochloride Specification
|Characteristics||White or almost white crystalline powder||White crystalline powder|
|Loss on drying||≤0.5%||0.32%|
|Assay(on drled basis)||≥99.5%||99.61%|
4) Mechanism of Actions
The mechanism through which affects premature ejaculation is still unclear. However, it is presumed that works by inhibiting serotonin transporter and subsequently increasing serotonin's action at pre and postsynaptic receptors Human ejaculation is regulated by various areas in the central nervous system (CNS). The ejaculatory pathway originates from spinal reflex at the thoracolumbar and lumbosacral level of spinal cord activated by stimuli from male genital. These signals are relayed to the brain stem, which then is influenced by a number of nuclei in the brain such as medial preoptic and paraventricular nulcei. Clement's study performed on anaesthetized male rats showed that acute administration of inhibits ejaculatory expulsion reflex at supraspinal level by modulating activity of lateral paragigantocellular nucleus (LPGi) neurons. These effects cause an increase in pudendal motoneuron reflex discharge (PMRD) latency. However, it is unclear whether acts directly on LPGi or on the descending pathway in which LPGi located.
5) Order Guide
Q1: Do you Accept Sample Order?
A: Yes, we accept small order from 10g, 100g and 1kg for your evaluation quality of our goods.
Q2: Is there any discount?
A: Yes, for larger quantity, we always support with better price. But if you have need small quantity for many products together, discount is also available.
Q3:How long does it take to the goods arrived ?
A: It is Depending on your location, let's talk in details.
For small order, please expect 5-7 days by DHL,UPS,TNT, FEDEX, EMS.
For mass order, please allow 5-8 days by Air, 20-35 days by Sea.
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