Suzhou Excellentbiotech Co.,Ltd

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Safety / High Purity Avanafil 330784-47-9 , Sex Steroid Hormone GMP Enterprise Standard

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Safety / High Purity Avanafil 330784-47-9 , Sex Steroid Hormone GMP Enterprise Standard

Safety / High Purity Avanafil 330784-47-9 , Sex Steroid Hormone GMP Enterprise Standard
Safety / High Purity Avanafil 330784-47-9 , Sex Steroid Hormone GMP Enterprise Standard Safety / High Purity Avanafil 330784-47-9 , Sex Steroid Hormone GMP Enterprise Standard Safety / High Purity Avanafil 330784-47-9 , Sex Steroid Hormone GMP Enterprise Standard Safety / High Purity Avanafil 330784-47-9 , Sex Steroid Hormone GMP Enterprise Standard

Large Image :  Safety / High Purity Avanafil 330784-47-9 , Sex Steroid Hormone GMP Enterprise Standard Get Best Price

Product Details:
Place of Origin: Wuhan
Brand Name: Excellentbiotech
Certification: SGS,ISO9001,HKAS,GMP
Model Number: 330784-47-9
Payment & Shipping Terms:
Minimum Order Quantity: Negotiation
Price: Negotiation
Packaging Details: Discreet ways of packing for Customs pass guaranteed
Delivery Time: Within 8 hous after receiving your payment
Payment Terms: T/T, , ,Bitcoin
Supply Ability: 5000Kg Per Month
Detailed Product Description
Product Name: Avanafil Assay: 99% Min.
CAS: 330784-47-9 MF: C23H26ClN7O3
MW: 483.9506 Melting Point: 150-152°C
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Sex Enhancing Drugs Safety And High Purity Avanafil 330784-47-9 Sex Steroid Hormone Powder

 

 

Product Details:

 

Synonyms: (S)-2-(2-Hydroxymethyl-1-pyrrolidinyl)-4-(3-chloro-4-methoxybenzylamino)-5-[(2-pyrimidinylmethyl)carbamoyl]pyrimidine;4-[(3-Chloro-4-methoxybenzyl)amino]-2-[2-(hydroxymethyl)-1-pyrrolidinyl]-N-(2-pyrimidinylmethyl)-5-pyrimidinecarboxamide;Avanafil;Avanafil (usan/inn);D03217;4-[[(3-Chloro-4-Methoxyphenyl)Methyl] aMino]-2-[(2S)-2-(hydroxyMethyl)-1-pyrrolidinyl]-N-(2-pyriMidinylMethyl)-5-pyriMidinecarboxaMide;4-((3-chloro-4-Methoxybenzyl)aMino)-2-(2-(hydroxyMethyl)pyrrolidin-1-yl)-N-(pyriMidin-2-ylMethyl)pyriMidine-5-carboxaMide;(S)-4-((3-Chloro-4-Methoxybenzyl)aMino)-2-(2-(hydroxyMethyl)pyrrolidin-1-yl)-N-(pyriMidin-2-ylMethyl)pyriMidine-5-carboxaMide

Assay: 99% min.

CAS: 330784-47-9

Molecular Formula:C23H26ClN7O3
Molecular Weight:483.9506

Molecular Structure:


Sex Change Drugs Safety And High Purity Avanafil 330784-47-9 Sex Steroid Hormone Powder
Character: White to Off-White Cyrstalline Solid.

Usage: Used for the treatment of erectile dysfunction. A phosphodiesterase 5 inhibitor.

Categories: Active Pharmaceutical Ingredients; Cnbio; Erectile Dysfunction; Inhibitors; Intermediates & Fine Chemicals; Pharmaceuticals; API's.

Certificates:SGS,ISO 9001, GMP

MOQ:10 gram

Provide Samples: Yes.

Delivery time: Within 8 hours upon receipt of payment

Payment method: T/T,, , bitcoins, bank transfer

Price: Factory price(Negociable)
Packing: Discreet and Disguised packing to pass the customs.
Delivery methods: EMS, DHL, TNT, FedEx, UPS,etc door to door.

Standard: GMP Enterprise standard.

The min. order is 10 grams.

Export Markets:Global

Storage: Shading, Confined Preservation
Usage:Used for the treatment of erectile dysfunction. A phosphodiesterase 5 inhibitor

 

 

Description:

 

Avanafil is a PDE5 inhibitor approved for erectile dysfunction by FDA on April 27, 2014, and by EMA on June 21, 2015. Avanafil acts by inhibiting a specific phosphodiesterase type 5 enzyme which is found in various body tissues, but primarily in the corpus cavernosum penis, as well as the retina. Other similar drugs are tadalafil and vardenafil. The advantage of avanafil is that it has the very fast onset of action compared with other PDE5 inhibitors.It is absorbed quickly. reaching a maximum concentration in about 30-45 minutes. About two-thirds of the participants were able to engage in sexual activity within 15 minutes.

 

 

Usage:


It is a development of the phosphodiesterase type 5 inhibitors, for the treatment of male sexual dysfunction, at present in the America, EU and Japan have completed phase II clinical trials, phase III clinical trials will start. The product is composed of Japanese Tanabe Pharma Company and VIVUS company development. In addition to oral dosage forms, VIVUS company is also developing Avanafil urethral administration, for not responding to oral dosage forms of patients.

Avanafil is a potent, highly selective phosphodiesterase 5 inhibitor, in vitro experiments showed that the selectivity of phosphodiesterase 5 stronger than . The compound dear compliance weak against other phosphodiesterase, and effect of adenosine receptor decreased, suggesting that the cardiovascular effects of avanafil should be weaker than .

Pre clinical study showed that avanafil and organic nitrate drugs taken in combination to reduce its on blood pressure was significantly weaker than and nitrate drugs with clothes. Moreover, avanafil inhibition of phosphodiesterase 6 is very weak, the relevant visual disturbance suppression may the enzyme phosphodiesterase 5 inhibitor induced and other.

 

 

COA:

 

COA:

 


Test Items

Specification

Test Results

Description

White or off-white crystalline powder

Off-white crystalline powder

Specific rotation

-56°~-60°

-58.2°

Identification

IR

Matches with working standard

Complies

HPLC

Solubility

Freely soluble in chloroform and in alcohol; Very slightly soluble in water

Conform

Heavy metals

≤10ppm

<10ppm

Water

≤0.3%

0.22%

Residue on ignition

≤0.1%

0.05%

Relative material

Maximum impurities≤0.5%

0.36%

Total impurities≤1.0%

0.52%

Assay

98.5~101.0%

99.68%

Conclusion

The specification conform with Enterprise standard

 

 

Application:

 

The advantage of avanafil is that it has very fast onset of action compared with other PDE5 inhibitors. It is absorbed quickly, reaching a maximum concentration in about 30-45 minutes.About two-thirds of the participants were able to engage in sexual activity within 15 minutes.

 

 

Superiority:


1. High purity and good quality
2. Professional and discreet packing
3. Fast delivery
4. High success rate to pass customs

 

 

Our Promise:

(1) High passing rate.
Professional team special for package and shipment and staring on tracking code 24hours for customs pass guaranteed.

(2) Factory Supply, Save intermediate cost, so our price is competitive and parcel can be sent out in 24 hours after payment. Tracking number is available.

(3) We have clients throughout the world.
Professional service and rich experience make customers feel at ease, adequate stock and fast delivery meet their desire.

(4) Good service.
Tell the package update ASAP, and will try best solve when customer encountered various problems.

(5) Discount is possible if order is enough.

 

 

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Test Propionate 57-85-2 Methnolone Enanthate 330-42-4
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Tes Phenylpropionate 1255-49-8 dianabol 72-63-9
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Test Decanoate 5721-91-5 Clomifene Citrate 50-41-9
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Stanolone 521-18-6 Tadalafil 171596-29-5
17-Methyl-test 58-18-4 Dutasteride 164656-23-9
4-Chlorotestosterone Acetate 85-19-6 Yohimbine HCI 65-19-0
Oral Turinabol 2446-23-3 Trenbolone Enanthate 10161-33-8
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Nandrolone phenylpropionate 62-90-8 MT-1 75921-69-6
Tren 10161-33-8 Melanotan-2 121062-08-6
Tren Acetate 10161-34-9 GHRP-2 158861-67-7
Ghrp-6 87616-84-0 Ipamorelin 170851-70-4
Hexarelin 140703-51-1 Sermorelin 86168-78-7
Oxytocin 158861-67-7 PT141 87616-84-0

 

 

 

Contact Details
Suzhou Excellentbiotech Co.,Ltd

Contact Person: lisa

Tel: +8613798562250

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