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Orlistat Fat Loss Pharmaceutical Orlistat for Loss Weight CAS: 96829-58-2
Product name: Orlistat
CAS Numbers: 96829-58-2
Appearance: white needle crystal or powder
Packing specification: 1 kg/bag
Melting point: 45°
Appearance: White or kind of white crystalline powder, soluble in water.
Usage: Used for curing obesity.
What is Orlistat?
Orlistat is a white to off-white crystalline powder. Orlistat is practically insoluble in water, freely soluble in chloroform, and very soluble in methanol and ethanol. Orlistat has no pKa within the physiological pH range.
Orlistat is a drug that promotes loss of weight by preventing the digestion and absorption of fat in food. In the intestine, an enzyme called lipase (produced primarily by the pancreas) breaks apart fat in food so that it can be absorbed into the body. Orlistat blocks the action of lipase and thereby prevents the breakup and absorption of fat. Orlistat blocks absorption of about 25% of the fat in a meal. The unabsorbed fat is excreted in the stool. The FDA approved Orlistat by prescription in 1999.
Orlistat (also known as tetrahydrolipstatin) is a drug designed to treat obesity. It is marketed as a prescription drug under the trade by Roche in most countries, and is sold over-the-counter as Alli by GlaxoSmithKline in the United Kingdom and the United States.Its primary function is preventing the absorption of fats from the human diet by acting as a lipase inhibitor, thereby reducing caloric intake. It is intended for use in conjunction with a healthcare provider-supervised reduced-calorie diet.
Orlistat is the saturated derivative of lipstatin, a potent natural inhibitor of pancreatic lipases isolated from the bacterium Streptomyces toxytricini.However, due to its relative simplicity and stability, orlistat was chosen over lipstatin for development as an anti-obesity drug.
The effectiveness of orlistat in promoting weight loss is definite, though modest. Pooled data from clinical trials suggest that people given orlistat in addition to lifestyle modifications, such as diet and exercise, lose about 2-3 kilograms (4.4-6.6 lb) more than those not taking the drug over the course of a year.Orlistat also modestly reduces blood pressure, and appears to prevent the onset of type 2 diabetes, whether due to weight loss itself or to other effects; in a large randomized controlled trial, orlistat was found to reduce the incidence of diabetes by nearly 40% in obese people.
Orlistat is notorious for its gastrointestinal side effects (sometimes referred to as treatment effects), which can include steatorrhea (oily, loose stools). These decrease with time, however, and are the most frequently reported adverse effects of the drug.In the United States and the European Union, orlistat is available for sale without a prescription. Over-the-counter approval was controversial in the United States, with consumer advocacy group Public Citizen repeatedly opposing it on safety and efficacy grounds.Generic formulations of orlistat are available in some countries. In Australia it is listed as an S3 medication, which means it's available over the counter in pharmacies.
|Description||White or almost crystalline powder||White crystalline powder|
|Specific rotation||-33 -35°||-34°|
|Loss on drying||<0.5%||0.35%|
|Assay(HPLC)||>=96.0%(ON DRY BASIS)||97.4%|
|Price||negotiable according to how many do you need|
|Payment Term||TT/West Union /Bitcoin/|
|Delivery Time||normally 5-10 days by express|
|Shipping way||Express(EMS,DHL,TNT,FedEX;HKDHL;EUB) Door to Door
Transport by air for large quantity.
|Shipping Time||Most countries can arrived within 3-10 days|
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We are the manufacturer of all kinds of hormone powders. We focus on providing customers with high quality products, competitive price, best service and timely delivery. Price: Please let us know the quantity you required, because for small order and bulk purchase, the price will be difference. Payment methods: , We will supply the receiver's information or the bank account information for payment use. Shipping items: Shipping items will be delivered by international express like EMS, TNT, UPS, FedEx or DHL after receiving received. Every item will be shipped out in 2-3 working days after the payment is done. The product usually arrives in 1-4 days based on the different destination, and online track is provided. Please kindly supply the shipping address, contact and tel number for successful shipment. We are 100% confident of my shipment method, None of our previous packages has ever had any delivery issues.
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