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anti estrogen medication,
anti estrogen drugs
Orally Synthetic Female Hormones Anastrozole Arimidex CAS 120511-73-1
Arimidex (anastrozole) is the aromatase inhibitor of choice. Arimidex’s mechanism of action — blocking conversion of aromatizable steroids to estrogen — is in contrast to the mechanism of action of anti-estrogens such as clomiphene (Clomid) or tamoxifen (Nolvadex), which block estrogen receptors in some tissues, and activate estrogen receptors in others.
CAS No: 120511-73-1
Appearance: white powder.
High Purity Anastrozole/Arimidex/CAS No: 120511-73-1
The drug is appropriately used when using substantial amounts of aromatizing steroids, or when one is prone to gynecomastia and using moderate amounts of such steroids. Arimidex does not have the side effects of aminoglutethimide (Cytadren) and can achieve a high degree of estrogen blockade, much moreso than Cytadren. It is possible to reduce estrogen too much with Arimidex, and for this reason blood tests, or less preferably salivary tests, should be taken after the first week of use to determine if the dosing is correct.
|Description||White crystalline powder||Complies|
Conform with standard IR
Conform with standard HPLC
|Solubility||Freely soluble in methanol,acetone,ethanol and tetrahydrofuran.And very soluble in acetonitrile||Complies|
|Total Unspecified Impurity||max. 0.2%||0.08%|
|Individual unspecified impurlty||max. 0.1%||0.05%|
|Related compound B||max. 0.2%||0.07%|
|Related compound C||max. 0.2%||0.04%|
|Related compound D||max. 0.1%||0.05%|
|Related compound E||max. 0.1%||0.06%|
|Limit of cyclohexane||max. 0.08%||ND|
|Limit of ethylacetate||max. 0.1%||0.07%|
|Residue on ignition||max. 0.1%||0.07%|
|Storage||Cool and dry|
|Conclusion||It complies to USP32 .|
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