Suzhou Excellentbiotech Co.,Ltd

Top Grade Biotechnology Manufacturer In China

Quality Product Safe Delivery Professional Service

Home
Products
About Us
Factory Tour
Quality Control
Contact Us
Request A Quote
News
Home ProductsPharmaceutical Raw Materials

Acetphenetidin for Analgesic powder Pharmaceutical Raw Materials Phenaceti

I'm Online Chat Now
China Suzhou Excellentbiotech Co.,Ltd certification
China Suzhou Excellentbiotech Co.,Ltd certification
Everything is perfect!The quality,prices and shipping!I will buy from you every month.

—— Carlos

The package is complete when i have it!Everything are perfect!Thank you Corleone and i will be keeping ordering!!

—— Blaker

Acetphenetidin for Analgesic powder Pharmaceutical Raw Materials Phenaceti

Acetphenetidin for Analgesic powder Pharmaceutical Raw Materials Phenaceti
Acetphenetidin for Analgesic powder Pharmaceutical Raw Materials Phenaceti Acetphenetidin for Analgesic powder Pharmaceutical Raw Materials Phenaceti

Large Image :  Acetphenetidin for Analgesic powder Pharmaceutical Raw Materials Phenaceti Get Best Price

Product Details:
Place of Origin: Wuhan
Brand Name: Excellentbiotech
Certification: SGS,ISO9001,UKAS,GMP
Model Number: 62-44-2
Payment & Shipping Terms:
Minimum Order Quantity: 10g
Price: Negotiable
Packaging Details: Discreet ways of packing for customs guaranteed
Delivery Time: Within 24 hours after payment
Payment Terms: T/T, , ,Bitcoin,Paypal
Supply Ability: 2000kg Per Month
Detailed Product Description
MF: C10H13NO2 MW: 179.22
Purity: 99.5% Appearance: White Powder
Grade: Pharmaceutical Grade Packing:: Aluminum Foil Bag
High Light:

pharmaceutical grade anabolic steroids

,

active pharmaceutical ingredients

Acetphenetidin for Analgesic powder Pharmaceutical Raw Materials Phenaceti

 

 

Phenacetin
 
Melting point 133-136 °C(lit.)
Boiling point 132 °C / 4mmHg
storage temp. 2-8°C
form powder
Water Solubility 0.076 g/100 mL
Sensitive Hygroscopic
Merck 14,7204
BRN 1869238
Stability: Stable. Incompatible with strong oxidizing agents, strong acids.
 
Product Name: Phenacetin
Synonyms:  4-ACETOPHENETIDIDE;4-acetophenetidine
CAS:  62-44-2
MF:

C10H13NO2Acetphenetidin for Analgesic powder Pharmaceutical Raw Materials Phenaceti 0

MW: 179.22
EINECS: 200-533-0
Garde:  Pharmaceutical grade
Content:  99%
Appearance:  white powder
Heading: 80
Packing:  aluminum foil bag
Ingredients: acetoethoxy aniline
 
Acetphenetidin for Analgesic powder Pharmaceutical Raw Materials Phenaceti 1
 
Uses
 
1. Used for organic synthesis of raw materials and drug intermediates from acetaminophen ether.
2. Antipyretic analgesics for the treatment of fever, headache, neuralgia.
3. Active pharmaceutical ingredient for Scientific Research.
 
 
Antipyretic analgesics
 
The antipyretic and analgesic effects of phenacetin are similar to that of acetylsalicylic acid, which is mainly used as anti-inflammatory drugs with a slow and long-lasting effect. It is an effective drug on the treatment of headache, neuralgia, joint pain and fever. However, it has a weak effect on treating anti-rheumatic, anti-inflammatory. Overdose can cause methemoglobinemia, resulting in hypoxia. Long-term medication can damage the kidneys, and even cause papillary necrosis, thus it should be taken with caution. Owing to its side effect and the rapid development of other similar drugs, the drug has been discontinued alone and just used as an active pharmaceutical ingredient for compound preparation with other drugs. It is often combined with aspirin, caffeine, for making aspirin compound (0.162 g of non-phenacetin, 0.227 g of aspirin, and 0.035 g of caffeine) for the treatment of colds with a small toxicity. Further addition of a small amount of the chlorpheniramine can produce chlorpheniramine cold tablets which can be applied to the treatment of colds, headache, neuralgia, rheumatism and so on.
 
 
Methods of Production
 
(1) By acetylation reaction from a p-aminophenyl ether. Heat the mixture of benzene, acetic anhydride and amino benzene ether on an oil bath azeotropically for 4h. Then cool the reaction mixture after completion of the reaction, getting precipitate of statins. Filter, washed with cold benzene and then dry to get the final product. The yield usually can reach 86% of the theoretical amount.
 
(2) By the reaction of sodium ethoxide and acetamidophenol: first add acetamidophenol into sodium ethoxide, and then slowly add ethyl iodide to heat and reflux for 1h, cool, filter, and the dissolve the crude product in ethanol. Filter and dilute the filtrate with water, and then cool, filter, and dried to obtain the final product. The yield can be 80% of the theoretical amount. At the first method, we can also use acetate instead of benzene as the solvent with the following process: heat 40% diluted acetic acid to boiling, add phenetidine and distill off the water. Add acetate when the temperature rise to 150 °C, reflux for 1h and continue to steam until the temperature rises above 150 °C, do sampling for determination of free amino benzene ether. Add certain amount of acetic anhydride based on the amount of residual phenetidine acetic anhydride, and the subject to reflux reaction for another 0.5h. Check the end, and reduce pressure if the product is qualified. Recycle acetate until the product contains 0.046 or less amino content and 0.2% or less acid. Press the reaction mixture back into the hot refined mother liquor, cool the mixture to 40 °C through stirring, filtrate and get the phenacetin crude product. For refining, add boiling water or refined mother liquor to phenacetin crude product, dissolve it through heated stirring, filter, and adjust the filtrate to pH = 4.5-4.7 with acid. Add activated carbon and sodium thiosulfates to stir for bleaching, filter and cool and crystal the filtrate liquid cooling crystallization, apply it to rejection filter, air dried to obtain phenacetin final product.

Phenacetin

 

Contact Details
Suzhou Excellentbiotech Co.,Ltd

Contact Person: lisa

Tel: +8613798562250

Send your inquiry directly to us